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Studies such as the LEADER trial (liraglutide), SUSTAIN-6 (semaglutide), and REWIND (dulaglutide) have shown reductions in major adverse cardiovascular events, including heart attack and stroke, in people with type 2 diabetes and established cardiovascular disease or high cardiovascular risk

Therapies that do not cause any change in the host genome include the use of non-coding RNA (nc-RNA) antisense oligonucleotides (ASO), RNA editing, and gene delivery

Immunity 42 , 406417, doi: 10.1016/j.immuni.2015.02.002 (2015)

Weight-Maintenance Coaching leads at 34.0%

2022 Oct 1;150(4 Suppl ):41S-48S

doi: 10.1007/s10735-007-9145-y van der Klaauw, A.A., Keogh, J.M., Henning, E., Trowse, V.M., Dhillo, W.S., Ghatei, M.A